Can you reconcile (professional) ambition with buddhism?

I have been a practicioner of mindfulness and vipassana for a few years. I have felt that buddhism is at odds with striving towards professional success and ambition. Ambition and professional success inherently has elements of attachment and passion, which are at odds with the fundamental virtues of buddhism (such as equanimity). On one hand, I would like to be my best self in professional life and make significant contributions to my field, but when I have this mindset I experience negative emotions like insecurity, impatience. Do you think that these two things are at odds with each other and if not, why?