Saints: Are they always comfortable in society? (Catholic Church perspective)

I know saints are exceptional, but I wonder how they could bear some people who are everything they are not. Could someone be a saint while being asocial, or a bit misanthropic? I know some saints were hermits or prefered to be alone, but to what extent could they do this without contradicting the Gospel and its teaching? My question is mainly about: Are there some examples of these kind of saints in the history of the Catholic Church?