Who were the Blessed Virgin Mother's enemies while she lived on earth?

Christ was reviled, scorned, derided, calumniated, and mocked while He lived on earth. If the Blessed Virgin Mother is one of the greatest imitators of Christ, it seems she likewise would've suffered these crosses, but there is no mention of this in Holy Scriptures. Besides Satan*, who were the Blessed Virgin Mother's enemies while she lived on earth, according to Catholic theologians, mystics' visions, or apocryphal accounts? *cf. Gen. 3:15 : "I will put enmities between thee [Satan] and the woman [the Blessed Virgin], and thy seed and her seed [Christ]: she [the Blessed Virgin] shall crush thy head, and thou shalt lie in wait for her heel."