how do I let go of everything?

Is there practice that I can do that will help me dissolve my attatchment to the world, my family, my life any hopes and dreams, its all transient and causes massive suffering for me. How can I let go of those who I cant remove who abuse me, those who I love who are leaving me, those things I wanted to create that will never happen? Its just so tiring to hold on to all this pain.