Fundamental building blocks of reality according to Buddhism?

Is there any mention of the fundamental building blocks of reality in Buddhism? Science tells us that we are made of atoms, which in turn are made of protons, neutrons and electrons, which in turn are made of quarks and so on. Does Buddhism reveal to us the absolute fundamental building blocks of reality and the Universe? If so, then what is the nature of those building blocks? I am 100% certain that the Buddha would have known the deepest nature of physical reality and answers to all the mysteries, humans have spent pondering since millenium. I know this question falls under the imponderable and thus doesn't aid me in relieving suffering in samsara, but still curious to know :) Peace.