Is Scientific Realism/Materialism and/or Historicity compatible with Mahayana?

In my estimation the answer is decidedly **no**, but I am interested to hear what others think from a Mahayana or Madhyamaka perspective. First, to try and clarify terms I am using scientific realism/materialism as described here: - Scientific Realism - Scientific Materialism - Historicity While the above links do a pretty good job of describing these worldviews I don't think they are perfect. In my own imperfect language I'd say these worldviews presuppose an objective world that exists in an independent and inherent manner. I think this is the default worldview of most lowly beings and certainly of western or modern society. The idea is that the practice of science gets us ever closer to the true and fundamental underlying material reality with the presupposition that there *is* a true and fundamental underlying material reality that exists in the first place. In this worldview, the laws of physics inherently exist and everything can be reduced to some fundamental building blocks of nature evolving in time according to those laws. That there is a truth of the matter about every historical event that is independent of any subjective consciousness. In short, that things exist inherently and not as mere conventions. To my mind, anyone who believes in these worldviews has not fully grokked the deep and subtle meaning of Mahayana/Madhyamaka emptiness. To be clear, I am not talking about the *practice* of science which I see as *distinct* from the worldviews above. To define by way of contrast, consider this alternative scientific worldview that does not presuppose an underlying observer independent physical reality. By the way, here is an article written by the author of Relational QM on the comparison of his work to Nagarjuna. Is this correct? What have I gotten wrong?